Morphine Induces Desensitization of Insulin Receptor Signaling

Morphine analgesia is mediated principally by the μ-opioid receptor (MOR). Since morphine and other opiates have been shown to influence glucose homeostasis, we investigated the hypothesis of direct cross talk between the MOR and the insulin receptor (IR) signaling cascades. We show that prolonged m...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Li, Yu, Eitan, Shoshana, Wu, Jiong, Evans, Christopher J., Kieffer, Brigitte, Sun, Xiaojian, Polakiewicz, Roberto D.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2003
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180943/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12917346/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.17.6255-6266.2003
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Morphine Induces Desensitization of Insulin Receptor Signaling

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