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Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein
Insulin stimulates glucose transport by promoting translocation of the insulin-sensitive glucose transporter isoform 4 (GLUT4) from an intracellular compartment to the cell surface. This movement is accomplished by stimulation of GLUT4 exocytosis as well as inhibition of endocytosis. However, the mo...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC60828/ https://ncbi.nlm.nih.gov/pubmed/11687655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241368698 |
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