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Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein

Insulin stimulates glucose transport by promoting translocation of the insulin-sensitive glucose transporter isoform 4 (GLUT4) from an intracellular compartment to the cell surface. This movement is accomplished by stimulation of GLUT4 exocytosis as well as inhibition of endocytosis. However, the mo...

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Detalhes bibliográficos
Main Authors: Huang, Jie, Imamura, Takeshi, Olefsky, Jerrold M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60828/
https://ncbi.nlm.nih.gov/pubmed/11687655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241368698
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