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Morphine Induces Desensitization of Insulin Receptor Signaling

Morphine analgesia is mediated principally by the μ-opioid receptor (MOR). Since morphine and other opiates have been shown to influence glucose homeostasis, we investigated the hypothesis of direct cross talk between the MOR and the insulin receptor (IR) signaling cascades. We show that prolonged m...

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Publicat a:Mol Cell Biol
Autors principals: Li, Yu, Eitan, Shoshana, Wu, Jiong, Evans, Christopher J., Kieffer, Brigitte, Sun, Xiaojian, Polakiewicz, Roberto D.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180943/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12917346/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.17.6255-6266.2003
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