Evaluation of the Activities of Pyrimethamine Analogs against Plasmodium vivax and Plasmodium falciparum Dihydrofolate Reductase-Thymidylate Synthase Using In Vitro Enzyme Inhibition and Bacterial Complementation Assays

Pyrimethamine analogs were examined as potential agents against vivax malaria using a bacterial surrogate system carrying Plasmodium vivax dihydrofolate reductase-thymidylate synthase (PvDHFR-TS), in which the PvDHFR complemented chemically knocked out host dihydrofolate reductase. The system was in...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Bunyarataphan, Sasinee , Leartsakulpanich, Ubolsree, Taweechai, Supannee, Tarnchompoo, Bongkoch, Kamchonwongpaisan, Sumalee, Yuthavong, Yongyuth
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2006
נושאים:
Susceptibility
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635237/
https://ncbi.nlm.nih.gov/pubmed/16954316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00448-06
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים