Evaluation of the Activities of Pyrimethamine Analogs against Plasmodium vivax and Plasmodium falciparum Dihydrofolate Reductase-Thymidylate Synthase Using In Vitro Enzyme Inhibiti...

Por Bunyarataphan, Sasinee , Leartsakulpanich, Ubolsree, Taweechai, Supannee, Tarnchompoo, Bongkoch, Kamchonwongpaisan, Sumalee, Yuthavong, Yongyuth
Publicado em 2006

Combined Spatial Limitation around Residues 16 and 108 of Plasmodium falciparum Dihydrofolate Reductase Explains Resistance to Cycloguanil

Por Vanichtanankul, Jarunee, Taweechai, Supannee, Uttamapinant, Chayasith, Chitnumsub, Penchit, Vilaivan, Tirayut, Yuthavong, Yongyuth, Kamchonwongpaisan, Sumalee
Publicado em 2012

Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target

Por Yuthavong, Yongyuth, Tarnchompoo, Bongkoch, Vilaivan, Tirayut, Chitnumsub, Penchit, Kamchonwongpaisan, Sumalee, Charman, Susan A., McLennan, Danielle N., White, Karen L., Vivas, Livia, Bongard, Emily, Thongphanchang, Chawanee, Taweechai, Supannee, Vanichtanankul, Jarunee, Rattanajak, Roonglawan, Arwon, Uthai, Fantauzzi, Pascal, Yuvaniyama, Jirundon, Charman, William N., Matthews, David
Publicado em 2012

Preclinical Evaluation of the Antifolate QN254, 5-Chloro- N′6′-(2,5-Dimethoxy-Benzyl)-Quinazoline-2,4,6-Triamine, as an Antimalarial Drug Candidate

Por Nzila, Alexis, Rottmann, Matthias, Chitnumsub, Penchit, Kiara, Stevens M., Kamchonwongpaisan, Sumalee, Maneeruttanarungroj, Cherdsak, Taweechai, Supannee, Yeung, Bryan K. S., Goh, Anne, Lakshminarayana, Suresh B., Zou, Bin, Wong, Josephine, Ma, Ngai Ling, Weaver, Margaret, Keller, Thomas H., Dartois, Veronique, Wittlin, Sergio, Brun, Reto, Yuthavong, Yongyuth, Diagana, Thierry T.
Publicado em 2010