Integrative analysis of RNA binding proteins identifies DDX55 as a novel regulator of 3’UTR isoform diversity

Abstract Background The 3’ untranslated regions (3’UTRs) of mRNAs play a critical role in controlling gene expression and function because they contain binding sites for microRNAs and RNA binding proteins (RBPs) that alter mRNA stability, localization, and translation. Most mRNA 3’ ends contain mult...

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Bibliografische gegevens
Hoofdauteurs: Matthew R. Gazzara, Timothy Cater, Michael J. Mallory, Yoseph Barash, Kristen W. Lynch
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2025-11-01
Reeks:Genome Biology
Onderwerpen:
Alternative Polyadenylation
DDX55
3’UTR
RNA Regulation
Online toegang:https://doi.org/10.1186/s13059-025-03852-8
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