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Integrative analysis of RNA binding proteins identifies DDX55 as a novel regulator of 3’UTR isoform diversity

Abstract Background The 3’ untranslated regions (3’UTRs) of mRNAs play a critical role in controlling gene expression and function because they contain binding sites for microRNAs and RNA binding proteins (RBPs) that alter mRNA stability, localization, and translation. Most mRNA 3’ ends contain mult...

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Principais autores: Matthew R. Gazzara, Timothy Cater, Michael J. Mallory, Yoseph Barash, Kristen W. Lynch
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-11-01
Serier:Genome Biology
Fag:
Alternative Polyadenylation
DDX55
3’UTR
RNA Regulation
Online adgang:https://doi.org/10.1186/s13059-025-03852-8
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