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Integrative analysis of RNA binding proteins identifies DDX55 as a novel regulator of 3’UTR isoform diversity

Abstract Background The 3’ untranslated regions (3’UTRs) of mRNAs play a critical role in controlling gene expression and function because they contain binding sites for microRNAs and RNA binding proteins (RBPs) that alter mRNA stability, localization, and translation. Most mRNA 3’ ends contain mult...

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Egile Nagusiak: Matthew R. Gazzara, Timothy Cater, Michael J. Mallory, Yoseph Barash, Kristen W. Lynch
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2025-11-01
Saila:Genome Biology
Gaiak:
Alternative Polyadenylation
DDX55
3’UTR
RNA Regulation
Sarrera elektronikoa:https://doi.org/10.1186/s13059-025-03852-8
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