Integrative analysis of RNA binding proteins identifies DDX55 as a novel regulator of 3’UTR isoform diversity

Abstract Background The 3’ untranslated regions (3’UTRs) of mRNAs play a critical role in controlling gene expression and function because they contain binding sites for microRNAs and RNA binding proteins (RBPs) that alter mRNA stability, localization, and translation. Most mRNA 3’ ends contain mult...

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Autors principals:	Matthew R. Gazzara, Timothy Cater, Michael J. Mallory, Yoseph Barash, Kristen W. Lynch
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-11-01
Col·lecció:	Genome Biology
Matèries:	Alternative Polyadenylation DDX55 3’UTR RNA Regulation
Accés en línia:	https://doi.org/10.1186/s13059-025-03852-8
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