DDX3 depletion represses translation of mRNAs with complex 5′ UTRs

DDX3 is an RNA chaperone of the DEAD-box family that regulates translation. Ded1, the yeast ortholog of DDX3, is a global regulator of translation, whereas DDX3 is thought to preferentially affect a subset of mRNAs. However, the set of mRNAs that are regulated by DDX3 are unknown, along with the rel...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Calviello, Lorenzo, Venkataramanan, Srivats, Rogowski, Karol J, Wyler, Emanuel, Wilkins, Kevin, Tejura, Malvika, Thai, Bao, Krol, Jacek, Filipowicz, Witold, Landthaler, Markus, Floor, Stephen N
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136831/
https://ncbi.nlm.nih.gov/pubmed/33905506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab287
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