Integrative analysis of RNA binding proteins identifies DDX55 as a novel regulator of 3’UTR isoform diversity

Abstract Background The 3’ untranslated regions (3’UTRs) of mRNAs play a critical role in controlling gene expression and function because they contain binding sites for microRNAs and RNA binding proteins (RBPs) that alter mRNA stability, localization, and translation. Most mRNA 3’ ends contain mult...

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Autores principales:	Matthew R. Gazzara, Timothy Cater, Michael J. Mallory, Yoseph Barash, Kristen W. Lynch
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-11-01
Colección:	Genome Biology
Materias:	Alternative Polyadenylation DDX55 3’UTR RNA Regulation
Acceso en línea:	https://doi.org/10.1186/s13059-025-03852-8
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