Integrative analysis of RNA binding proteins identifies DDX55 as a novel regulator of 3’UTR isoform diversity

Abstract Background The 3’ untranslated regions (3’UTRs) of mRNAs play a critical role in controlling gene expression and function because they contain binding sites for microRNAs and RNA binding proteins (RBPs) that alter mRNA stability, localization, and translation. Most mRNA 3’ ends contain mult...

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主要な著者:	Matthew R. Gazzara, Timothy Cater, Michael J. Mallory, Yoseph Barash, Kristen W. Lynch
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-11-01
シリーズ:	Genome Biology
主題:	Alternative Polyadenylation DDX55 3’UTR RNA Regulation
オンライン･アクセス:	https://doi.org/10.1186/s13059-025-03852-8
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