Transcriptional activity regulates alternative cleavage and polyadenylation

Abstract Genes containing multiple pre‐mRNA cleavage and polyadenylation sites, or polyA sites, express mRNA isoforms with variable 3′ untranslated regions (UTRs). By systematic analysis of human and mouse transcriptomes, we found that short 3′UTR isoforms are relatively more abundant when genes are...

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Detalles Bibliográficos

Principais autores:	Zhe Ji, Wenting Luo, Wencheng Li, Mainul Hoque, Zhenhua Pan, Yun Zhao, Bin Tian
Formato:	Artigo
Idioma:	Inglês
Publicado:	Springer Nature 2011-09-01
Series:	Molecular Systems Biology
Assuntos:	3′ end processing 3′UTR alternative polyadenylation post‐transcriptional control transcription
Acceso en liña:	https://doi.org/10.1038/msb.2011.69
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