IL-6 and MYC collaborate in plasma cell tumor formation in mice

Por Rutsch, Sebastian, Neppalli, Vishala T., Shin, Dong-Mi, DuBois, Wendy, Morse, Herbert C., Goldschmidt, Hartmut, Janz, Siegfried
Publicado em 2010

Mndal, a new interferon-inducible family member, is highly polymorphic, suppresses cell growth, and may modify plasmacytoma susceptibility

Por Zhang, Ke, Kagan, Daniel, DuBois, Wendy, Robinson, Richard, Bliskovsky, Valery, Vass, William C., Zhang, Shuling, Mock, Beverly A.
Publicado em 2009

3’Igh enhancers hs3b/hs4 are dispensable for Myc deregulation in mouse plasmacytomas with T(12;15) translocations

Por Kovalchuk, Alexander L., Sakai, Tomomi, Qi, Chen-Feng, Du Bois, Wendy, Dunnick, Wesley A., Cogné, Michel, Morse, Herbert C.
Publicado no Oncotarget (2018)

Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene

Por Bliskovsky, Valery, Ramsay, Edward S., Scott, John, DuBois, Wendy, Shi, Wei, Zhang, Shuling, Qian, Xiaolan, Lowy, Douglas R., Mock, Beverly A.
Publicado em 2003

The transcription factor MZF1 differentially regulates murine Mtor promoter variants linked to tumor susceptibility

Por Zhang, Shuling, Shi, Wei, Ramsay, Edward S., Bliskovsky, Valery, Eiden, Adrian Max, Connors, Daniel, Steinsaltz, Matthew, DuBois, Wendy, Mock, Beverly A.
Publicado no J Biol Chem (2019)

CDDO-Imidazolide inhibits growth and survival of c-Myc-induced mouse B cell and plasma cell neoplasms

Por Han, Seong-Su, Peng, Liangping, Chung, Seung-Tae, DuBois, Wendy, Maeng, Sung-Ho, Shaffer, Arthur L, Sporn, Michael B, Janz, Siegfried
Publicado em 2006

Mouse tumor susceptibility genes identify drug combinations for multiple myeloma

Por Zhang, Shuling, DuBois, Wendy, Zhang, Ke, Simmons, John K., Hughitt, V. Keith, Gorjifard, Sayeh, Gaikwad, Snehal, Peat, Tyler J., Mock, Beverly A.
Publicado no J Cancer Metastasis Treat (2020)

Efficiency Alleles of the Pctr1 Modifier Locus for Plasmacytoma Susceptibility

Por Zhang, Shuling-L., DuBois, Wendy, Ramsay, Edward S., Bliskovski, Valeri, Morse, Herbert C., Taddesse-Heath, Leki, Vass, William C., DePinho, Ronald A., Mock, Beverly A.
Publicado em 2001

Global gene expression profiling in mouse plasma cell tumor precursor and bystander cells reveals potential intervention targets for plasma cell neoplasia

Por LeGrand, Jason, Park, Eun Sung, Wang, Hongyang, Gupta, Shalu, Owens, James D., Nelson, Patrick J., DuBois, Wendy, Bair, Thomas, Janz, Siegfried, Mushinski, J. Frederic
Publicado em 2012

Susceptibility to Anthrax Lethal Toxin Is Controlled by Three Linked Quantitative Trait Loci

Por McAllister, Ryan D., Singh, Yogendra, du Bois, Wendy D., Potter, Michael, Boehm, Thomas, Meeker, Nathan D., Fillmore, Parley D., Anderson, Lisa M., Poynter, Matthew E., Teuscher, Cory
Publicado em 2003

mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells

Por Smrž, Daniel, Kim, Mi-Sun, Zhang, Shuling, Mock, Beverly A., Smržová, Šárka, DuBois, Wendy, Simakova, Olga, Maric, Irina, Wilson, Todd M., Metcalfe, Dean D., Gilfillan, Alasdair M.
Publicado em 2011

AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements

Por Kovalchuk, Alexander L., duBois, Wendy, Mushinski, Elizabeth, McNeil, Nicole E., Hirt, Carsten, Qi, Chen-Feng, Li, Zhaoyang, Janz, Siegfried, Honjo, Tasuku, Muramatsu, Masamichi, Ried, Thomas, Behrens, Timothy, Potter, Michael
Publicado em 2007

Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production

Por Zhang, Shuling, Readinger, Julie A., DuBois, Wendy, Janka-Junttila, Mirkka, Robinson, Richard, Pruitt, Margaret, Bliskovsky, Val, Wu, Julie Z., Sakakibara, Kaori, Patel, Jyoti, Parent, Carole A., Tessarollo, Lino, Schwartzberg, Pamela L., Mock, Beverly A.
Publicado em 2011

ATP-degrading ENPP1 is required for survival (or persistence) of long-lived plasma cells

Por Wang, Hongsheng, Gonzalez-Garcia, Ines, Traba, Javier, Jain, Shweta, Conteh, Solomon, Shin, Dong-Mi, Qi, Chenfeng, Gao, Yuanyuan, Sun, Jiafang, Kang, Sungyun, Abbasi, Sadia, Naghashfar, Zohreh, Yoon, Jeongheon, DuBois, Wendy, Kovalchuk, Alexander L., Sack, Michael N., Duffy, Patrick, Morse, Herbert C.
Publicado no Sci Rep (2017)

Increased mammalian lifespan and a segmental and tissue-specific slowing of aging following genetic reduction of mTOR expression

Por Wu, J. Julie, Liu, Jie, Chen, Edmund B., Wang, Jennifer J., Cao, Liu, Narayan, Nisha, Fergusson, Marie M., Rovira, Ilsa I., Allen, Michele, Springer, Danielle A., Lago, Cory U., Zhang, Shuling, DuBois, Wendy, Ward, Theresa, deCabo, Rafael, Gavrilova, Oksana, Mock, Beverly, Finkel, Toren
Publicado em 2013

Cooperative Targets of Combined mTOR/HDAC Inhibition Promote MYC Degradation

Por Simmons, John K., Michalowski, Aleksandra M., Gamache, Benjamin J., DuBois, Wendy, Patel, Jyoti, Zhang, Ke, Gary, Joy, Zhang, Shuling, Gaikwad, Snehal, Connors, Daniel, Watson, Nicholas, Leon, Elena, Chen, Jin-Qiu, Kuehl, W. Michael, Lee, Maxwell P., Zingone, Adriana, Landgren, Ola, Ordentlich, Peter, Huang, Jing, Mock, Beverly A.
Publicado no Mol Cancer Ther (2017)

mTOR intersects antibody-inducing signals from TACI in marginal zone B cells

Por Sintes, Jordi, Gentile, Maurizio, Zhang, Shuling, Garcia-Carmona, Yolanda, Magri, Giuliana, Cassis, Linda, Segura-Garzón, Daniel, Ciociola, Alessandra, Grasset, Emilie K., Bascones, Sabrina, Comerma, Laura, Pybus, Marc, Lligé, David, Puga, Irene, Gutzeit, Cindy, He, Bing, DuBois, Wendy, Crespo, Marta, Pascual, Julio, Mensa, Anna, Aróstegui, Juan Ignacio, Juan, Manel, Yagüe, Jordi, Serrano, Sergi, Lloreta, Josep, Meffre, Eric, Hahne, Michael, Cunningham-Rundles, Charlotte, Mock, Beverly A., Cerutti, Andrea
Publicado no Nat Commun (2017)