The transcription factor MZF1 differentially regulates murine Mtor promoter variants linked to tumor susceptibility

Mechanistic target of rapamycin (MTOR) is a highly conserved serine/threonine kinase that critically regulates cell growth, proliferation, differentiation, and survival. Previously, we have implicated Mtor as a plasmacytoma-resistance locus, Pctr2, in mice. Here, we report that administration of the...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Zhang, Shuling, Shi, Wei, Ramsay, Edward S., Bliskovsky, Valery, Eiden, Adrian Max, Connors, Daniel, Steinsaltz, Matthew, DuBois, Wendy, Mock, Beverly A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Gene Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851318/
https://ncbi.nlm.nih.gov/pubmed/31548308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009779
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares