The transcription factor MZF1 differentially regulates murine Mtor promoter variants linked to tumor susceptibility

Mechanistic target of rapamycin (MTOR) is a highly conserved serine/threonine kinase that critically regulates cell growth, proliferation, differentiation, and survival. Previously, we have implicated Mtor as a plasmacytoma-resistance locus, Pctr2, in mice. Here, we report that administration of the...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Zhang, Shuling, Shi, Wei, Ramsay, Edward S., Bliskovsky, Valery, Eiden, Adrian Max, Connors, Daniel, Steinsaltz, Matthew, DuBois, Wendy, Mock, Beverly A.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2019
Sujets:
Gene Regulation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851318/
https://ncbi.nlm.nih.gov/pubmed/31548308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009779
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