3’Igh enhancers hs3b/hs4 are dispensable for Myc deregulation in mouse plasmacytomas with T(12;15) translocations

Myc-deregulating T(12;15) chromosomal translocations are the hallmark cytogenetic abnormalities of murine plasmacytomas (PCTs). In most PCTs, the immunoglobulin heavy chain (Igh) locus is broken between the Eμ enhancer and the 3’ regulatory region (3’RR), making the latter the major candidate for or...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Kovalchuk, Alexander L., Sakai, Tomomi, Qi, Chen-Feng, Du Bois, Wendy, Dunnick, Wesley A., Cogné, Michel, Morse, Herbert C.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2018
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195379/
https://ncbi.nlm.nih.gov/pubmed/30349647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26160
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