3’Igh enhancers hs3b/hs4 are dispensable for Myc deregulation in mouse plasmacytomas with T(12;15) translocations

Myc-deregulating T(12;15) chromosomal translocations are the hallmark cytogenetic abnormalities of murine plasmacytomas (PCTs). In most PCTs, the immunoglobulin heavy chain (Igh) locus is broken between the Eμ enhancer and the 3’ regulatory region (3’RR), making the latter the major candidate for or...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Kovalchuk, Alexander L., Sakai, Tomomi, Qi, Chen-Feng, Du Bois, Wendy, Dunnick, Wesley A., Cogné, Michel, Morse, Herbert C.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2018
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195379/
https://ncbi.nlm.nih.gov/pubmed/30349647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26160
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