3’Igh enhancers hs3b/hs4 are dispensable for Myc deregulation in mouse plasmacytomas with T(12;15) translocations

Myc-deregulating T(12;15) chromosomal translocations are the hallmark cytogenetic abnormalities of murine plasmacytomas (PCTs). In most PCTs, the immunoglobulin heavy chain (Igh) locus is broken between the Eμ enhancer and the 3’ regulatory region (3’RR), making the latter the major candidate for or...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Kovalchuk, Alexander L., Sakai, Tomomi, Qi, Chen-Feng, Du Bois, Wendy, Dunnick, Wesley A., Cogné, Michel, Morse, Herbert C.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2018
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195379/
https://ncbi.nlm.nih.gov/pubmed/30349647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26160
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