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Long-range Oncogenic Activation of IgH/c-myc Translocations by the IgH 3’ Regulatory Region

B cell malignancies, such as human Burkitt’s lymphoma (BL), often harbor translocations that link c-myc or other proto-oncogenes to the immunoglobulin heavy chain locus (IgH)1. The nature of elements that activate oncogenes within such translocations has been a longstanding question. Translocations...

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Main Authors: Gostissa, Monica, Yan, Catherine T., Bianco, Julia M., Cogné, Michel, Pinaud, Eric, Alt, Frederick W.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802177/
https://ncbi.nlm.nih.gov/pubmed/20010689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08633
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