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Cis-Regulatory Elements and Epigenetic Changes Control Genomic Rearrangements of the IgH Locus

Immunoglobulin variable region exons are assembled from discontinuous variable (V), diversity (D), and joining (J) segments by the process of V(D)J recombination. V(D)J rearrangements of the immunoglobulin heavy chain (IgH) locus are tightly controlled in a tissue-specific, ordered and allele-specif...

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Sonraí Bibleagrafaíochta
Main Authors: Perlot, Thomas, Alt, Frederick W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115588/
https://ncbi.nlm.nih.gov/pubmed/19117530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0065-2776(08)00601-9
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