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Cis-Regulatory Elements and Epigenetic Changes Control Genomic Rearrangements of the IgH Locus

Immunoglobulin variable region exons are assembled from discontinuous variable (V), diversity (D), and joining (J) segments by the process of V(D)J recombination. V(D)J rearrangements of the immunoglobulin heavy chain (IgH) locus are tightly controlled in a tissue-specific, ordered and allele-specif...

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Bibliografiska uppgifter
Huvudupphovsmän: Perlot, Thomas, Alt, Frederick W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115588/
https://ncbi.nlm.nih.gov/pubmed/19117530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0065-2776(08)00601-9
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