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Cis-Regulatory Elements and Epigenetic Changes Control Genomic Rearrangements of the IgH Locus
Immunoglobulin variable region exons are assembled from discontinuous variable (V), diversity (D), and joining (J) segments by the process of V(D)J recombination. V(D)J rearrangements of the immunoglobulin heavy chain (IgH) locus are tightly controlled in a tissue-specific, ordered and allele-specif...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3115588/ https://ncbi.nlm.nih.gov/pubmed/19117530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0065-2776(08)00601-9 |
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