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The IgH locus 3′ cis-regulatory super-enhancer co-opts AID for allelic transvection
Immunoglobulin heavy chain (IgH) alleles have ambivalent relationships: they feature both allelic exclusion, ensuring monoallelic expression of a single immunoglobulin (Ig) allele, and frequent inter-allelic class-switch recombination (CSR) reassembling genes from both alleles. The IgH locus 3′ regu...
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Publicado no: | Oncotarget |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Impact Journals LLC
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355067/ https://ncbi.nlm.nih.gov/pubmed/28088785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14585 |
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