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The IgH locus 3′ cis-regulatory super-enhancer co-opts AID for allelic transvection
Immunoglobulin heavy chain (IgH) alleles have ambivalent relationships: they feature both allelic exclusion, ensuring monoallelic expression of a single immunoglobulin (Ig) allele, and frequent inter-allelic class-switch recombination (CSR) reassembling genes from both alleles. The IgH locus 3′ regu...
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Pubblicato in: | Oncotarget |
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Autori principali: | , , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Impact Journals LLC
2017
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355067/ https://ncbi.nlm.nih.gov/pubmed/28088785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14585 |
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