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The zebrafish IgH locus contains multiple transcriptional regulatory regions

Many fish have, in addition to IgM and IgD, a third isotype called IgZ or IgT. The ζ-chain locus is embedded among the Ig heavy chain V-, D- and J-elements in a manner reminiscent of the TcR δ/α locus. Isotype selection thus occurs during VDJ recombination, a process that is facilitated by intralocu...

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Bibliografske podrobnosti
Main Authors: Danilova, N., Saunders, H. L., Ellestad, K. K., Magor, B. G.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031712/
https://ncbi.nlm.nih.gov/pubmed/21055416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dci.2010.10.010
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