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The zebrafish IgH locus contains multiple transcriptional regulatory regions
Many fish have, in addition to IgM and IgD, a third isotype called IgZ or IgT. The ζ-chain locus is embedded among the Ig heavy chain V-, D- and J-elements in a manner reminiscent of the TcR δ/α locus. Isotype selection thus occurs during VDJ recombination, a process that is facilitated by intralocu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031712/ https://ncbi.nlm.nih.gov/pubmed/21055416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dci.2010.10.010 |
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