Misregulation of the IgH Locus in Thymocytes

Functional antigen receptor genes are assembled by somatic rearrangements that are largely lymphocyte lineage specific. The immunoglobulin heavy chain (IgH) gene locus is unique amongst the seven antigen receptor loci in undergoing partial gene rearrangements in the wrong lineage. Here we demonstrat...

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Udgivet i:Front Immunol
Main Authors: Kumari, Gita, Gerasimova, Tatiana, Du, Hansen, De, Supriyo, Wood, William H., Becker, Kevin G., Sen, Ranjan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6244664/
https://ncbi.nlm.nih.gov/pubmed/30483245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02426
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