A T cell controlled molecular pathway regulating the IgH locus: CD40-mediated activation of the IgH 3' enhancer.

Immunoglobulin heavy chain (IgH) class switch recombination and regulation of IgH expression levels are processes suggested to be controlled by the IgH 3' enhancer. Here we demonstrate that CD40 or IgM receptor stimulation of primary B cells results in transactivation of this enhancer. 4-Hydrox...

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Autori principali: Grant, P A, Andersson, T, Neurath, M F, Arulampalam, V, Bauch, A, Müller, R, Reth, M, Pettersson, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC452493/
https://ncbi.nlm.nih.gov/pubmed/8978695
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