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mTOR intersects antibody-inducing signals from TACI in marginal zone B cells
Mechanistic target of rapamycin (mTOR) enhances immunity in addition to orchestrating metabolism. Here we show that mTOR coordinates immunometabolic reconfiguration of marginal zone (MZ) B cells, a pre-activated lymphocyte subset that mounts antibody responses to T-cell-independent antigens through...
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Publicado no: | Nat Commun |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5684130/ https://ncbi.nlm.nih.gov/pubmed/29133782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01602-4 |
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