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TACI Isoforms Regulate Ligand Binding and Receptor Function
TACI signals activate B cell proliferation, isotype switch and antibody production in both normal immunity and autoimmune states. In contrast to murine TACI, the human TACI gene undergoes alternative splicing to produce short and long isoforms (TACI-S and TACI-L). In previous studies, we showed that...
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| Publicado no: | Front Immunol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6176016/ https://ncbi.nlm.nih.gov/pubmed/30333819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02125 |
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