TACI Isoforms Regulate Ligand Binding and Receptor Function

TACI signals activate B cell proliferation, isotype switch and antibody production in both normal immunity and autoimmune states. In contrast to murine TACI, the human TACI gene undergoes alternative splicing to produce short and long isoforms (TACI-S and TACI-L). In previous studies, we showed that...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Garcia-Carmona, Yolanda, Ting, Adrian T., Radigan, Lin, Athuluri Divakar, Sai Krishna, Chavez, Jose, Meffre, Eric, Cerutti, Andrea, Cunningham-Rundles, Charlotte
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176016/
https://ncbi.nlm.nih.gov/pubmed/30333819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02125
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