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TACI mutations and impaired B-cell function in subjects with CVID and healthy heterozygotes

BACKGROUND: Mutations in the gene coding for the transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) are found in 8% to 10% of subjects with common variable immunodeficiency (CVID). Although heterozygous mutations may coincide with immunodeficiency in a few families,...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Martinez-Gallo, Monica, Radigan, Lin, Almejún, María Belén, Martínez-Pomar, Natalia, Matamoros, Núria, Cunningham-Rundles, Charlotte
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646641/
https://ncbi.nlm.nih.gov/pubmed/23237420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.10.029
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