CVID-associated TACI mutations affect autoreactive B cell selection and activation

Common variable immune deficiency (CVID) is an assorted group of primary diseases that clinically manifest with antibody deficiency, infection susceptibility, and autoimmunity. Heterozygous mutations in the gene encoding the tumor necrosis factor receptor superfamily member TACI are associated with...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Romberg, Neil, Chamberlain, Nicolas, Saadoun, David, Gentile, Maurizio, Kinnunen, Tuure, Ng, Yen Shing, Virdee, Manmeet, Menard, Laurence, Cantaert, Tineke, Morbach, Henner, Rachid, Rima, Martinez-Pomar, Natalia, Matamoros, Nuria, Geha, Raif, Grimbacher, Bodo, Cerutti, Andrea, Cunningham-Rundles, Charlotte, Meffre, Eric
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2013
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786721/
https://ncbi.nlm.nih.gov/pubmed/24051380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69854
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