CVID-associated TACI mutations affect autoreactive B cell selection and activation

Common variable immune deficiency (CVID) is an assorted group of primary diseases that clinically manifest with antibody deficiency, infection susceptibility, and autoimmunity. Heterozygous mutations in the gene encoding the tumor necrosis factor receptor superfamily member TACI are associated with...

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Detaylı Bibliyografya
Asıl Yazarlar: Romberg, Neil, Chamberlain, Nicolas, Saadoun, David, Gentile, Maurizio, Kinnunen, Tuure, Ng, Yen Shing, Virdee, Manmeet, Menard, Laurence, Cantaert, Tineke, Morbach, Henner, Rachid, Rima, Martinez-Pomar, Natalia, Matamoros, Nuria, Geha, Raif, Grimbacher, Bodo, Cerutti, Andrea, Cunningham-Rundles, Charlotte, Meffre, Eric
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786721/
https://ncbi.nlm.nih.gov/pubmed/24051380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69854
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