Innate lymphoid cells integrate stromal and immune signals to enhance antibody production by splenic marginal zone B cells

Innate lymphoid cells (ILCs) regulate stromal, epithelial and immune cells, but their impact on B cells remains unclear. We identified RORγt(+) ILCs nearby the marginal zone (MZ), a splenic compartment containing innate-like B cells that respond to circulating T cell-independent (TI) antigens. Speni...

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Main Authors: Magri, Giuliana, Miyajima, Michio, Bascones, Sabrina, Mortha, Arthur, Puga, Irene, Cassis, Linda, Barra, Carolina M., Comerma, Laura, Chudnovskiy, Aleksey, Gentile, Maurizio, Llige, David, Cols, Montserrat, Serrano, Sergi, Aróstegui, Juan Ignacio, Juan, Manel, Yagüe, Jordi, Merad, Miriam, Fagarasan, Sidonia, Cerutti, Andrea
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005806/
https://ncbi.nlm.nih.gov/pubmed/24562309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2830
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