CDDO-Imidazolide inhibits growth and survival of c-Myc-induced mouse B cell and plasma cell neoplasms

BACKGROUND: Gene-targeted iMyc(Eμ )mice that carry a His(6)-tagged mouse Myc(c-myc)cDNA, Myc(His), just 5' of the immunoglobulin heavy-chain enhancer, Eμ, are prone to B cell and plasma cell neoplasms, such as lymphoblastic B-cell lymphoma (LBL) and plasmacytoma (PCT). Cell lines derived from M...

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Autores principales: Han, Seong-Su, Peng, Liangping, Chung, Seung-Tae, DuBois, Wendy, Maeng, Sung-Ho, Shaffer, Arthur L, Sporn, Michael B, Janz, Siegfried
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1553469/
https://ncbi.nlm.nih.gov/pubmed/16759389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-5-22
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