Susceptibility to Anthrax Lethal Toxin Is Controlled by Three Linked Quantitative Trait Loci

Anthrax lethal toxin (LT) is the principal virulence factor associated with lethal pathologies following infection with Bacillus anthracis. Macrophages are the primary effector cells mediating lethality since macrophage-depleted mice are resistant to LT challenge. Recently, Ltxs1, the gene controlli...

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Detalhes bibliográficos
Main Authors: McAllister, Ryan D., Singh, Yogendra, du Bois, Wendy D., Potter, Michael, Boehm, Thomas, Meeker, Nathan D., Fillmore, Parley D., Anderson, Lisa M., Poynter, Matthew E., Teuscher, Cory
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892420/
https://ncbi.nlm.nih.gov/pubmed/14578173
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