mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells

Increased mast cell burden is observed in the inflamed tissues and affected organs and tissues of patients with mast cell proliferative disorders. However, normal mast cells participate in host defense, so approaches to preferentially target clonally expanding mast cells are needed. We found that ma...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Smrž, Daniel, Kim, Mi-Sun, Zhang, Shuling, Mock, Beverly A., Smržová, Šárka, DuBois, Wendy, Simakova, Olga, Maric, Irina, Wilson, Todd M., Metcalfe, Dean D., Gilfillan, Alasdair M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2011
Ämnen:
Immunobiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245204/
https://ncbi.nlm.nih.gov/pubmed/22053105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-359984
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk