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Activation and function of the mTORC1 pathway in mast cells

Little is known about the signals downstream of phosphoinositide 3-kinase (PI3K) which regulate mast cell homeostasis and function following FcεRI aggregation and Kit ligation. Here, we investigated the role of the mammalian target of rapamycin complex 1 (mTORC1) pathway in these responses. In human...

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Autori principali: Kim, Mi-Sun, Kuehn, Hye Sun, Metcalfe, Dean D., Gilfillan, Alasdair M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698706/
https://ncbi.nlm.nih.gov/pubmed/18354181
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