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Synergistic activation of phospholipases Cγ and Cβ: A novel mechanism for PI3K-independent enhancement of FcεRI-induced mast cell mediator release

Antigen/IgE-mediated mast cell activation via FcεRI can be markedly enhanced by the activation of other receptors expressed on mast cells and these receptors may thus contribute to the allergic response in vivo. One such receptor family is the G protein-coupled receptors (GPCRs). Although the signal...

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Detalhes bibliográficos
Main Authors: Kuehn, Hye Sun, Beaven, Michael A., Ma, Hong-Tao, Kim, Mi-Sun, Metcalfe, Dean D., Gilfillan, Alasdair M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692074/
https://ncbi.nlm.nih.gov/pubmed/18207701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2007.11.016
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