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Rictor negatively regulates FcεRI-induced mast cell degranulation

Rictor is a regulatory component of the mammalian target of rapamycin (mTOR) complex 2 (mTORC2). We have previously demonstrated that rictor expression is substantially down-regulated in terminally differentiated mast cells as compared to their immature or transformed counterparts. However, it is no...

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Smrz, Daniel, Cruse, Glenn, Beaven, Michael A., Kirshenbaum, Arnold, Metcalfe, Dean D., Gilfillan, Alasdair M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258480/
https://ncbi.nlm.nih.gov/pubmed/25378594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303495
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