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Concurrent inhibition of Kit- and FcεRI-mediated signaling: Coordinated suppression of mast cell activation
Although primarily required for the growth, differentiation, and survival of mast cells, Kit ligand (stem cell factor) is also required for optimal antigen-mediated mast cell activation. Therefore, concurrent inhibition of Kit- and FcεRI-mediated signaling would be an attractive approach for targeti...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692100/ https://ncbi.nlm.nih.gov/pubmed/17925481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.107.125237 |
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