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Concurrent inhibition of Kit- and FcεRI-mediated signaling: Coordinated suppression of mast cell activation

Although primarily required for the growth, differentiation, and survival of mast cells, Kit ligand (stem cell factor) is also required for optimal antigen-mediated mast cell activation. Therefore, concurrent inhibition of Kit- and FcεRI-mediated signaling would be an attractive approach for targeti...

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Bibliografische gegevens
Hoofdauteurs: Jensen, Bettina M., Beaven, Michael A., Iwaki, Shoko, Metcalfe, Dean D., Gilfillan, Alasdair M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692100/
https://ncbi.nlm.nih.gov/pubmed/17925481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.107.125237
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