Btk-dependent Rac activation and actin rearrangement following FcεRI aggregation promotes enhanced chemotactic responses of mast cells

Mast cells infiltrate the sites of inflammation associated with chronic atopic disease and during helminth and bacterial infection. This process requires receptor-mediated cell chemotaxis across a concentration gradient of their chemotactic ligands. In vivo, mast cells are likely to be exposed to se...

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Detaylı Bibliyografya
Asıl Yazarlar: Kuehn, Hye Sun, Rådinger, Madeleine, Brown, Jared M., Ali, Khaled, Vanhaesebroeck, Bart, Beaven, Michael A., Metcalfe, Dean D., Gilfillan, Alasdair M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Company of Biologists 2010
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908047/
https://ncbi.nlm.nih.gov/pubmed/20587594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.071043
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