Btk-dependent Rac activation and actin rearrangement following FcεRI aggregation promotes enhanced chemotactic responses of mast cells

Mast cells infiltrate the sites of inflammation associated with chronic atopic disease and during helminth and bacterial infection. This process requires receptor-mediated cell chemotaxis across a concentration gradient of their chemotactic ligands. In vivo, mast cells are likely to be exposed to se...

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Autores principales: Kuehn, Hye Sun, Rådinger, Madeleine, Brown, Jared M., Ali, Khaled, Vanhaesebroeck, Bart, Beaven, Michael A., Metcalfe, Dean D., Gilfillan, Alasdair M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Company of Biologists 2010
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908047/
https://ncbi.nlm.nih.gov/pubmed/20587594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.071043
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