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G Protein-coupled receptors and the modification of FcεRI-mediated mast cell activation

By releasing multiple pro-inflammatory mediators upon activation, mast cells are critical effector cells in the pathogenesis of allergic inflammation. The traditional viewpoint of antigen-dependent mast cell activation is that of a Th(2)-driven process whereby antigen-specific IgE molecules are prod...

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Detalhes bibliográficos
Main Authors: Kuehn, Hye Sun, Gilfillan, Alasdair M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094129/
https://ncbi.nlm.nih.gov/pubmed/17919738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2007.08.007
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