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IgE-FcεRI Interactions Determine HIV Coreceptor Usage and Susceptibility to Infection during Ontogeny of Mast Cells

Progenitor mast cells (prMCs), derived from CD34(+) precursors are CD4(+)/CCR5(+)/CXCR4(+) and susceptible to CCR5(R5)-tropic virus but only marginally susceptible to CXCR4(X4)-tropic HIV. As infected prMCs mature within extravascular compartments, they become both latently infected and HIV-infectio...

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Bibliographic Details
Main Authors: Sundstrom, J. Bruce, Hair, Gregory A., Ansari, Aftab A., Secor, W. Evan, Gilfillan, Alasdair M., Metcalfe, Dean D., Kirshenbaum, Arnold S.
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791323/
https://ncbi.nlm.nih.gov/pubmed/19414793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0801481
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