EBAG9 tempers lymphocyte killing activity

por Ménasché, Gaël, de Saint Basile, Geneviève
Publicado 2009

Cytotoxic granule secretion by lymphocytes and its link to immune homeostasis

por de Saint Basile, Geneviève, Sepulveda, Fernando E., Maschalidi, Sophia, Fischer, Alain
Publicado en F1000Res (2015)

Graded Defects in Cytotoxicity Determine Severity of Hemophagocytic Lymphohistiocytosis in Humans and Mice

por Jessen, Birthe, Kögl, Tamara, Sepulveda, Fernando E., de Saint Basile, Genevieve, Aichele, Peter, Ehl, Stephan
Publicado 2013

Late‐onset hemophagocytic lymphohistiocytosis with neurological presentation

por Benezech, Sarah, Walzer, Thierry, Charrier, Emily, Heidelberg, Damien, De Saint‐Basile, Geneviève, Bertrand, Yves, Belot, Alexandre
Publicado en Clin Case Rep (2017)

Munc13-4*rab27 complex tethers secretory lysosomes at the plasma membrane

por Elstak, Edo D., Neeft, Maaike, Nehme, Nadine T., Callebaut, Isabelle, de Saint Basile, Geneviève, van der Sluijs, Peter
Publicado 2012

Defective CTLA-4 cycling pathway in Chediak–Higashi syndrome: A possible mechanism for deregulation of T lymphocyte activation

por Barrat, Franck J., Le Deist, Françoise, Benkerrou, Malika, Bousso, Philippe, Feldmann, Jérome, Fischer, Alain, de Saint Basile, Geneviève
Publicado 1999

Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex

por Kurowska, Mathieu, Goudin, Nicolas, Nehme, Nadine T., Court, Magali, Garin, Jérôme, Fischer, Alain, de Saint Basile, Geneviève, Ménasché, Gaël
Publicado 2012

Ttc7a regulates hematopoietic stem cell functions while controlling the stress-induced response

por Leveau, Claire, Gajardo, Tania, El-Daher, Marie-Thérèse, Cagnard, Nicolas, Fischer, Alain, de Saint Basile, Geneviève, Sepulveda, Fernando E.
Publicado en Haematologica (2020)

Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1, RAB27A, and STX11

por Sepulveda, Fernando E., Debeurme, Franck, Ménasché, Gaël, Kurowska, Mathieu, Côte, Marjorie, Schmid, Jana Pachlopnik, Fischer, Alain, de Saint Basile, Geneviève
Publicado 2013

Griscelli syndrome restricted to hypopigmentation results from a melanophilin defect (GS3) or a MYO5A F-exon deletion (GS1)

por Ménasché, Gaël, Hsuan Ho, Chen, Sanal, Ozden, Feldmann, Jérôme, Tezcan, Ilhan, Ersoy, Fügen, Houdusse, Anne, Fischer, Alain, de Saint Basile, Geneviève
Publicado 2005

Deficient Peptide Loading and MHC Class II Endosomal Sorting in a Human Genetic Immunodeficiency Disease: the Chediak-Higashi Syndrome

por Faigle, Wolfgang, Raposo, Graça, Tenza, Daniele, Pinet, Valérie, Vogt, Anne B., Kropshofer, Harald, Fischer, Alain, de Saint-Basile, Geneviève, Amigorena, Sebastian
Publicado 1998

Efficacy of ruxolitinib in subcutaneous panniculitis-like T-cell lymphoma and hemophagocytic lymphohistiocytosis

por Lévy, Romain, Fusaro, Mathieu, Guerin, Frédéric, Chetouani, Ahmed, Moshous, Despina, Fischer, Alain, de Saint Basile, Geneviève, Sepulveda, Fernando E., Neven, Bénédicte
Publicado en Blood Adv (2020)

Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product

por Pasquier, Benoit, Yin, Luo, Fondanèche, Marie-Claude, Relouzat, Francis, Bloch-Queyrat, Coralie, Lambert, Nathalie, Fischer, Alain, de Saint-Basile, Geneviève, Latour, Sylvain
Publicado 2005

Rab27a: A Key to Melanosome Transport in Human Melanocytes

por Bahadoran, Philippe, Aberdam, Edith, Mantoux, Frédéric, Buscà, Roser, Bille, Karine, Yalman, Nevin, de Saint-Basile, Geneviève, Casaroli-Marano, Ricardo, Ortonne, Jean-Paul, Ballotti, Robert
Publicado 2001

Diversity, functionality, and stability of the T cell repertoire derived in vivo from a single human T cell precursor

por Bousso, Philippe, Wahn, Volker, Douagi, Iyadh, Horneff, Gerd, Pannetier, Christophe, Le Deist, Françoise, Zepp, Fred, Niehues, Tim, Kourilsky, Philippe, Fischer, Alain, de Saint Basile, Geneviève
Publicado 2000

CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans

por Weller, Sandra, Faili, Ahmad, Garcia, Corinne, Braun, Moritz C., Le Deist, Françoise, de Saint Basile, Geneviève, Hermine, Olivier, Fischer, Alain, Reynaud, Claude-Agnès, Weill, Jean-Claude
Publicado 2001

Neutralization of IFNγ defeats haemophagocytosis in LCMV-infected perforin- and Rab27a-deficient mice

por Schmid, Jana Pachlopnik, Ho, Chen-H, Chrétien, Fabrice, Lefebvre, Juliette M, Pivert, Gérard, Kosco-Vilbois, Marie, Ferlin, Walter, Geissmann, Frédéric, Fischer, Alain, de Saint Basile, Geneviève
Publicado 2009

Gene transfer into hematopoietic stem cells reduces HLH manifestations in a murine model of Munc13-4 deficiency

por Soheili, Tayebeh, Durand, Amandine, Sepulveda, Fernando E., Rivière, Julie, Lagresle-Peyrou, Chantal, Sadek, Hanem, de Saint Basile, Geneviève, Martin, Samia, Mavilio, Fulvio, Cavazzana, Marina, André-Schmutz, Isabelle
Publicado en Blood Adv (2017)

Dynamic Formation of Microvillus Inclusions During Enterocyte Differentiation in Munc18-2–Deficient Intestinal Organoids

por Mosa, Mohammed H., Nicolle, Ophélie, Maschalidi, Sophia, Sepulveda, Fernando E., Bidaud-Meynard, Aurelien, Menche, Constantin, Michels, Birgitta E., Michaux, Grégoire, de Saint Basile, Geneviève, Farin, Henner F.
Publicado en Cell Mol Gastroenterol Hepatol (2018)

Kinesin-1 regulates antigen cross-presentation through the scission of tubulations from early endosomes in dendritic cells

por Belabed, Meriem, Mauvais, François-Xavier, Maschalidi, Sophia, Kurowska, Mathieu, Goudin, Nicolas, Huang, Jian-Dong, Fischer, Alain, de Saint Basile, Geneviève, van Endert, Peter, Sepulveda, Fernando E., Ménasché, Gaël
Publicado en Nat Commun (2020)