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EBAG9 tempers lymphocyte killing activity

The cytotoxic activity of lymphocytes is crucial for immune surveillance and homeostasis. Several independent, naturally occurring genetic models characterized by defects in granule trafficking or exocytosis have helped to decipher the multiple steps and molecules that regulate the cytotoxic process...

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Autori principali: Ménasché, Gaël, de Saint Basile, Geneviève
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719923/
https://ncbi.nlm.nih.gov/pubmed/19620775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40270
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