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The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8(+) T cells
CTLs eliminate virus-infected and tumorigenic cells through exocytosis of cytotoxic agents from lytic granules. While insights into the intracellular mechanisms facilitating lytic granule release have been obtained through analysis of loss-of-function mutations in humans and mice, there is a paucity...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719940/ https://ncbi.nlm.nih.gov/pubmed/19620783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37760 |
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