Neutralization of IFNγ defeats haemophagocytosis in LCMV-infected perforin- and Rab27a-deficient mice

Hereditary haemophagocytic lymphohistiocytosis (HLH) is a fatal inflammatory disease and treatments currently may lead to serious side effects. There is a pressing need for effective, less toxic treatments for this disease. Previous reports have suggested that interferon γ (IFNγ) has a role in the p...

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Bibliographische Detailangaben
Hauptverfasser: Schmid, Jana Pachlopnik, Ho, Chen-H, Chrétien, Fabrice, Lefebvre, Juliette M, Pivert, Gérard, Kosco-Vilbois, Marie, Ferlin, Walter, Geissmann, Frédéric, Fischer, Alain, de Saint Basile, Geneviève
Format: Artigo
Sprache:Inglês
Veröffentlicht: WILEY-VCH Verlag 2009
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378118/
https://ncbi.nlm.nih.gov/pubmed/20049711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.200900009
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