TLR8: No gain, no pain

per Barrat, Franck J.
Publicat a J Exp Med (2018)

A pathogenic role of plasmacytoid dendritic cells in autoimmunity and chronic viral infection

per Barrat, Franck J., Su, Lishan
Publicat a J Exp Med (2019)

Role of type I interferons and innate immunity in systemic sclerosis: unbalanced activities on distinct cell types?

per Barrat, Franck J., Lu, Theresa T.
Publicat a Curr Opin Rheumatol (2019)

Interferon target-gene expression and epigenomic signatures in health and disease

per Barrat, Franck J., Crow, Mary K., Ivashkiv, Lionel B.
Publicat a Nat Immunol (2019)

Ro60-Associated Single-Stranded RNA Links Inflammation with Fetal Cardiac Fibrosis via Ligation of TLRs: A Novel Pathway to Autoimmune-Associated Heart Block

per Clancy, Robert M., Alvarez, David, Komissarova, Elena, Barrat, Franck J., Swartz, Jordan, Buyon, Jill P.
Publicat 2010

Non-cytotoxic Inhibition of the Immunoproteasome Regulates Human Immune Cells in vitro and Suppresses Cutaneous Inflammation in the Mouse

per Kioon, Marie Dominique Ah, Pierides, Michael, Pannellini, Tania, Lin, Gang, Nathan, Carl F., Barrat, Franck J.
Publicat a J Immunol (2021)

Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9

per Guiducci, Cristiana, Tripodo, Claudio, Gong, Mei, Sangaletti, Sabina, Colombo, Mario P., Coffman, Robert L., Barrat, Franck J.
Publicat 2010

Defective CTLA-4 cycling pathway in Chediak–Higashi syndrome: A possible mechanism for deregulation of T lymphocyte activation

per Barrat, Franck J., Le Deist, Françoise, Benkerrou, Malika, Bousso, Philippe, Feldmann, Jérome, Fischer, Alain, de Saint Basile, Geneviève
Publicat 1999

Musculoskeletal Involvement in SSc Is Associated with Worse Scores on Short Form-36 and Scleroderma Health Assessment Questionnaire and Lower Tumor Necrosis Factor-α Gene Expressio...

per Pelrine, Eliza R., Ah-Kioon, Marie-Dominique, Zhang, Meng, Barrat, Franck J., Spiera, Robert F., Gordon, Jessica K.
Publicat a HSS J (2016)

Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus

per Barrat, Franck J., Meeker, Thea, Gregorio, Josh, Chan, Jean H., Uematsu, Satoshi, Akira, Shizuo, Chang, Bonnie, Duramad, Omar, Coffman, Robert L.
Publicat 2005

PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation

per Guiducci, Cristiana, Ghirelli, Cristina, Marloie-Provost, Marie-Annick, Matray, Tracy, Coffman, Robert L., Liu, Yong-Jun, Barrat, Franck J., Soumelis, Vassili
Publicat 2008

Self-RNA–antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8

per Ganguly, Dipyaman, Chamilos, Georgios, Lande, Roberto, Gregorio, Josh, Meller, Stephan, Facchinetti, Valeria, Homey, Bernhard, Barrat, Franck J., Zal, Tomasz, Gilliet, Michel
Publicat 2009

Interferon-α promotes abnormal vasculogenesis in lupus: a potential pathway for premature atherosclerosis

per Denny, Michael F., Thacker, Seth, Mehta, Hemal, Somers, Emily C., Dodick, Todd, Barrat, Franck J., McCune, W. Joseph, Kaplan, Mariana J.
Publicat 2007

Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation

per Guiducci, Cristiana, Ott, Gary, Chan, Jean H., Damon, Emily, Calacsan, Carlo, Matray, Tracy, Lee, Kyung-Dall, Coffman, Robert L., Barrat, Franck J.
Publicat 2006

Blocking TLR7- and TLR9-mediated IFN-α Production by Plasmacytoid Dendritic Cells Does Not Diminish Immune Activation in Early SIV Infection

per Kader, Muhamuda, Smith, Amanda P., Guiducci, Cristiana, Wonderlich, Elizabeth R., Normolle, Daniel, Watkins, Simon C., Barrat, Franck J., Barratt-Boyes, Simon M.
Publicat 2013

A Critical Role for Interleukin 18 in Primary and Memory Effector Responses to Listeria monocytogenes That Extends Beyond Its Effects on Interferon γ Production

per Neighbors, Margaret, Xu, Xiuling, Barrat, Franck J., Ruuls, Sigrid R., Churakova, Tatyana, Debets, Reno, Bazan, J. Fernando, Kastelein, Robert A., Abrams, John S., O'Garra, Anne
Publicat 2001

A Novel Role of Endothelin-1 in Linking Toll-like Receptor 7-mediated Inflammation to Fibrosis in Congenital Heart Block

per Alvarez, David, Briassouli, Paraskevi, Clancy, Robert M., Zavadil, Jiri, Reed, Joanne H., Abellar, Rosanna G., Halushka, Marc, Fox-Talbot, Karen, Barrat, Franck J., Buyon, Jill P.
Publicat 2011

RNA recognition by human TLR8 can lead to autoimmune inflammation

per Guiducci, Cristiana, Gong, Mei, Cepika, Alma-Martina, Xu, Zhaohui, Tripodo, Claudio, Bennett, Lynda, Crain, Chad, Quartier, Pierre, Cush, John J., Pascual, Virginia, Coffman, Robert L., Barrat, Franck J.
Publicat 2013

In Vitro Generation of Interleukin 10–producing Regulatory CD4(+) T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2-inducing Cytokines...

per Barrat, Franck J., Cua, Daniel J., Boonstra, André, Richards, David F., Crain, Chad, Savelkoul, Huub F., de Waal-Malefyt, René, Coffman, Robert L., Hawrylowicz, Catherine M., O'Garra, Anne
Publicat 2002

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

per Garcia-Romo, Gina S., Caielli, Simone, Vega, Barbara, Connolly, John, Allantaz, Florence, Xu, Zhaohui, Punaro, Marilynn, Baisch, Jeanine, Guiducci, Cristiana, Coffman, Robert L., Barrat, Franck J., Banchereau, Jacques, Pascual, Virginia
Publicat 2011