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Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9

Recognition of endogenous DNA and RNA by cells expressing TLR7 and TLR9 is an important contributor to the pathogenesis of systemic lupus erythematosus and has been suggested to contribute to cutaneous lupus and to a group of related inflammatory skin diseases termed interface dermatitis. We have de...

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Detalhes bibliográficos
Main Authors: Guiducci, Cristiana, Tripodo, Claudio, Gong, Mei, Sangaletti, Sabina, Colombo, Mario P., Coffman, Robert L., Barrat, Franck J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005224/
https://ncbi.nlm.nih.gov/pubmed/21115693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101048
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