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TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus

Glucocorticoids are widely used to treat patients with autoimmune diseases such as systemic lupus erythematosus (SLE)1,2. However, regimens used to treat many such conditions cannot maintain disease control in the majority of SLE patients and more aggressive approaches such as high-dose methylpredni...

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Bibliografske podrobnosti
Main Authors: Guiducci, Cristiana, Gong, Mei, Xu, Zhaohui, Gill, Michelle, Chaussabel, Damien, Meeker, Thea, Chan, Jean H., Wright, Tracey, Punaro, Marilynn, Bolland, Silvia, Soumelis, Vassili, Banchereau, Jacques, Coffman, Robert L., Pascual, Virginia, Barrat, Franck J.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964153/
https://ncbi.nlm.nih.gov/pubmed/20559388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09102
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