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TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus

Glucocorticoids are widely used to treat patients with autoimmune diseases such as systemic lupus erythematosus (SLE)1,2. However, regimens used to treat many such conditions cannot maintain disease control in the majority of SLE patients and more aggressive approaches such as high-dose methylpredni...

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書誌詳細
主要な著者: Guiducci, Cristiana, Gong, Mei, Xu, Zhaohui, Gill, Michelle, Chaussabel, Damien, Meeker, Thea, Chan, Jean H., Wright, Tracey, Punaro, Marilynn, Bolland, Silvia, Soumelis, Vassili, Banchereau, Jacques, Coffman, Robert L., Pascual, Virginia, Barrat, Franck J.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964153/
https://ncbi.nlm.nih.gov/pubmed/20559388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09102
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