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Munc13-4*rab27 complex tethers secretory lysosomes at the plasma membrane

Natural Killer (NK) cells and Cytotoxic T lymphocytes (CTL) are critical for the immune response against virus infections or transformed cells. They kill target cells via polarized exocytosis of lytic proteins from secretory lysosomes (SL). Rab27a and munc13-4 interact directly and are required for...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Elstak, Edo D., Neeft, Maaike, Nehme, Nadine T., Callebaut, Isabelle, de Saint Basile, Geneviève, van der Sluijs, Peter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291317/
https://ncbi.nlm.nih.gov/pubmed/22482013
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