Cytotoxic granule secretion by lymphocytes and its link to immune homeostasis

di de Saint Basile, Geneviève, Sepulveda, Fernando E., Maschalidi, Sophia, Fischer, Alain
Pubblicato in F1000Res (2015)

Graded Defects in Cytotoxicity Determine Severity of Hemophagocytic Lymphohistiocytosis in Humans and Mice

di Jessen, Birthe, Kögl, Tamara, Sepulveda, Fernando E., de Saint Basile, Genevieve, Aichele, Peter, Ehl, Stephan
Pubblicazione 2013

Ttc7a regulates hematopoietic stem cell functions while controlling the stress-induced response

di Leveau, Claire, Gajardo, Tania, El-Daher, Marie-Thérèse, Cagnard, Nicolas, Fischer, Alain, de Saint Basile, Geneviève, Sepulveda, Fernando E.
Pubblicato in Haematologica (2020)

Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1, RAB27A, and STX11

di Sepulveda, Fernando E., Debeurme, Franck, Ménasché, Gaël, Kurowska, Mathieu, Côte, Marjorie, Schmid, Jana Pachlopnik, Fischer, Alain, de Saint Basile, Geneviève
Pubblicazione 2013

Efficacy of ruxolitinib in subcutaneous panniculitis-like T-cell lymphoma and hemophagocytic lymphohistiocytosis

di Lévy, Romain, Fusaro, Mathieu, Guerin, Frédéric, Chetouani, Ahmed, Moshous, Despina, Fischer, Alain, de Saint Basile, Geneviève, Sepulveda, Fernando E., Neven, Bénédicte
Pubblicato in Blood Adv (2020)

Asparagine Endopeptidase Controls Anti-Influenza Virus Immune Responses through TLR7 Activation

di Maschalidi, Sophia, Hässler, Signe, Blanc, Fany, Sepulveda, Fernando E., Tohme, Mira, Chignard, Michel, van Endert, Peter, Si-Tahar, Mustapha, Descamps, Delphyne, Manoury, Bénédicte
Pubblicazione 2012

Gene transfer into hematopoietic stem cells reduces HLH manifestations in a murine model of Munc13-4 deficiency

di Soheili, Tayebeh, Durand, Amandine, Sepulveda, Fernando E., Rivière, Julie, Lagresle-Peyrou, Chantal, Sadek, Hanem, de Saint Basile, Geneviève, Martin, Samia, Mavilio, Fulvio, Cavazzana, Marina, André-Schmutz, Isabelle
Pubblicato in Blood Adv (2017)

Dynamic Formation of Microvillus Inclusions During Enterocyte Differentiation in Munc18-2–Deficient Intestinal Organoids

di Mosa, Mohammed H., Nicolle, Ophélie, Maschalidi, Sophia, Sepulveda, Fernando E., Bidaud-Meynard, Aurelien, Menche, Constantin, Michels, Birgitta E., Michaux, Grégoire, de Saint Basile, Geneviève, Farin, Henner F.
Pubblicato in Cell Mol Gastroenterol Hepatol (2018)

Kinesin-1 regulates antigen cross-presentation through the scission of tubulations from early endosomes in dendritic cells

di Belabed, Meriem, Mauvais, François-Xavier, Maschalidi, Sophia, Kurowska, Mathieu, Goudin, Nicolas, Huang, Jian-Dong, Fischer, Alain, de Saint Basile, Geneviève, van Endert, Peter, Sepulveda, Fernando E., Ménasché, Gaël
Pubblicato in Nat Commun (2020)

Chronic Intestinal Pseudo-Obstruction and Lymphoproliferative Syndrome as a Novel Phenotype Associated With Tetratricopeptide Repeat Domain 7A Deficiency

di El-Daher, Marie-Thérèse, Lemale, Julie, Bruneau, Julie, Leveau, Claire, Guerin, Frédéric, Lambert, Nathalie, Diana, Jean-Sébastien, Neven, Bénédicte, Sepulveda, Fernando E., Coulomb-L'Hermine, Aurore, Molina, Thierry, Picard, Capucine, Fischer, Alain, de Saint Basile, Geneviève
Pubblicato in Front Immunol (2019)

UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells

di Maschalidi, Sophia, Nunes-Hasler, Paula, Nascimento, Clarissa R, Sallent, Ignacio, Lannoy, Valérie, Garfa-Traore, Meriem, Cagnard, Nicolas, Sepulveda, Fernando E., Vargas, Pablo, Lennon-Duménil, Ana-Maria, van Endert, Peter, Capiod, Thierry, Demaurex, Nicolas, Darrasse-Jèze, Guillaume, Manoury, Bénédicte
Pubblicato in Nat Commun (2017)

Hemophagocytic Lymphohistiocytosis Gene Mutations in Adult Patients Presenting With CLIPPERS-Like Syndrome

di Taieb, Guillaume, Kaphan, Elsa, Duflos, Claire, Lebrun-Frénay, Christine, Rigau, Valérie, Thouvenot, Eric, Duhin-Gand, Emeline, Lefaucheur, Romain, Hoang-Xuan, Khe, Coulette, Sarah, Ouallet, Jean Christophe, Menjot de Champfleur, Nicolas, Tranchant, Christine, Picard, Capucine, Fusaro, Mathieu, Sepulveda, Fernando E., Labauge, Pierre, de Saint Basile, Geneviève
Pubblicato in Neurol Neuroimmunol Neuroinflamm (2021)

Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases

di Li, Yue, Führer, Marita, Bahrami, Ehsan, Socha, Piotr, Klaudel-Dreszler, Maja, Bouzidi, Amira, Liu, Yanshan, Lehle, Anna S., Magg, Thomas, Hollizeck, Sebastian, Rohlfs, Meino, Conca, Raffaele, Field, Michael, Warner, Neil, Mordechai, Slae, Shteyer, Eyal, Turner, Dan, Boukari, Rachida, Belbouab, Reda, Walz, Christoph, Gaidt, Moritz M., Hornung, Veit, Baumann, Bernd, Pannicke, Ulrich, Al Idrissi, Eman, Ali Alghamdi, Hamza, Sepulveda, Fernando E., Gil, Marine, de Saint Basile, Geneviève, Hönig, Manfred, Koletzko, Sibylle, Muise, Aleixo M., Snapper, Scott B., Schwarz, Klaus, Klein, Christoph, Kotlarz, Daniel
Pubblicato in Proc Natl Acad Sci U S A (2019)