UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells

Dendritic cells (DC) have the unique ability to present exogenous antigens via the major histocompatibility complex class I pathway to stimulate naive CD8(+) T cells. In DCs with a non-functional mutation in Unc93b1 (3d mutation), endosomal acidification, phagosomal maturation, antigen degradation,...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Maschalidi, Sophia, Nunes-Hasler, Paula, Nascimento, Clarissa R, Sallent, Ignacio, Lannoy, Valérie, Garfa-Traore, Meriem, Cagnard, Nicolas, Sepulveda, Fernando E., Vargas, Pablo, Lennon-Duménil, Ana-Maria, van Endert, Peter, Capiod, Thierry, Demaurex, Nicolas, Darrasse-Jèze, Guillaume, Manoury, Bénédicte
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696382/
https://ncbi.nlm.nih.gov/pubmed/29158474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01601-5
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky