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UNC93B1 mediates differential trafficking of endosomal TLRs

UNC93B1, a multipass transmembrane protein required for TLR3, TLR7, TLR9, TLR11, TLR12, and TLR13 function, controls trafficking of TLRs from the endoplasmic reticulum (ER) to endolysosomes. The mechanisms by which UNC93B1 mediates these regulatory effects remain unclear. Here, we demonstrate that U...

詳細記述

保存先:
書誌詳細
主要な著者: Lee, Bettina L, Moon, Joanne E, Shu, Jeffrey H, Yuan, Lin, Newman, Zachary R, Schekman, Randy, Barton, Gregory M
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576711/
https://ncbi.nlm.nih.gov/pubmed/23426999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00291
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